Apoptosis: BRCA1, CDKN2A, DAPK1, GSTP1, MGMT (AGT), PTEN, RUNX3, TIMP3, TP73, VHL.
|Human Tumor Suppressor Genes DNA Methylation PCR Array, Signature Panel: EAHS-551Z|
|The Human Tumor Suppressor Genes EpiTect Methyl II Signature PCR Array profiles the methylation status of 22 tumor suppressor gene promoters whose hypermethylation has been reported in the literature to occur frequently in a variety and types of cancers and tumors. Profiling tumor samples with these arrays may help correlate CpG island methylation status with biological phenotypes. The results may provide insights into the molecular mechanisms and biological pathways behind oncogenesis, as well as cancer pathology. With a simple restriction enzyme digestion and real-time PCR, research studies can analyze the methylation status of 22 different tumor suppressor genes with this DNA methylation PCR array.|
Both 96-well and 384-well ( 4 X 96 ) formats are available.
Cell Adhesion: APC, CDH1, CDH13, CDKN2A.
Cell Cycle: APC, BRCA1, CDKN2A, FHIT, MLH1, NEUROG1, PTEN, RASSF1, RUNX3, TP73, VHL.
DNA Damage & Repair: APC, BRCA1, MGMT (AGT), MLH1, TP73.
Signal Transduction: APC, BRCA1, CDH13, ESR1, PTEN, RASSF1, SOCS1, WIF1.
Transcription Factors: BRCA1, CDH1, ESR1, NEUROG1, RARB, RUNX3, TP73, VHL.
Other: PDLIM4 (RIL).